目的：评估新型眼前节分析仪MS-39与Sirius、Pentacam在测量角膜白到白（WTW）和中央前房深度（ACD）的一致性，并比较三种仪器用于可植入式眼内镜（ICL）尺寸选择的差异。 方法：回顾性病例研究。连续纳入2019年9月至2020年9月在西安交通大学第一附属医院眼科屈光手术中心就诊的患者210名（420眼），使用MS-39、Sirius和Pentacam三种眼前节分析系统分别测量WTW和ACD，比较三种仪器的测量结果。使用STAAR公司推荐方法模拟计算ICL V4c尺寸。采用Pearson相关分析法、组内相关系数和Bland-Altman分析法进行数据的相关性及一致性分析。 结果：MS-39、Sirius和Pentacam的WTW测量结果为11.39±0.35mm、11.42±0.36mm和11.46±0.35 mm。其中，MS-39测量值低于Pentacam（P=0.002），而MS-39与Sirius、Sirius与Pentacam的测量差异无统计学意义。三种设备WTW测量值呈高度正相关（MS-39与Sirius、MS-39与Pentacam、Sirius与Pentacam的r值为0.942、0.925、0.882，P＜0.0001）。ACD测量值分别为3.28±0.22mm（MS-39）、3.28±0.24mm（Sirius）和3.21±0.23mm（Pentacam），MS-39与Sirius测量结果差异无统计学意义，但均显著高于Pentacam（均P<0.0001）。三种设备ACD测量值呈高度正相关（MS-39与Sirius、MS-39与Pentacam、Sirius与Pentacam的r值为0.959、0.947、0.932，P<0.0001）。基于三种仪器的测量结果进行ICL尺寸选择时，均以12.6mm占比最高， 13.7mm占比最少，各仪器尺寸选择分布接近。 结论：MS-39对WTW和ACD的测量值与Sirius和Pentacam保持高度正相关性，结果可以相互替代。在ICL尺寸选择中，基于MS-39的选择结果与Sirius和Pentacam分布接近，在临床中具有一定的可行性。

Objective: To assess the consistency of the new anterior segment analyzer MS-39 with the Sirius and Pentacam in measuring corneal white to white (WTW) and central anterior chamber depth (ACD), and to compare their differences in guiding implantable collamer lens (ICL) size selection. Methods: We conducted a retrospective case study. This study enrolled 210 consecutive patients (420 eyes) who presented at the Ophthalmology Refractive Surgery Center of the First Affiliated Hospital of Xi'an Jiaotong University between September 2019 and September 2020. Three anterior segment analysis systems, MS-39, Sirius, and Pentacam, were utilized to assess the WTW and ACD, with comparative analysis of the results. The sizing of the ICL V4c was simulated using the method recommended by the STAAR company. Data correlation and consistency were evaluated using Pearson correlation analysis, intra-class correlation coefficients, and Bland-Altman analysis. Results: The WTW measurement results obtained from MS-39, Sirius, and Pentacam were 11.39±0.35mm, 11.42±0.36mm, and 11.46±0.35mm, respectively. Notably, the WTW measurement value from MS-39 was lower than that from Pentacam (P = 0.002), while no statistically significant differences were observed between MS-39 and Sirius, or between Sirius and Pentacam. The WTW measurements from the three devices exhibited a strong positive correlation, with correlation coefficients (r) of 0.942 between MS-39 and Sirius, 0.925 between MS-39 and Pentacam, and 0.882 between Sirius and Pentacam (both P < 0.0001). The ACD measurements values were 3.28±0.22mm (MS-39), 3.28±0.24mm (Sirius), and 3.21±0.23mm (Pentacam), respectively. While, no statistically significant difference was found between MS-39 and Sirius, both measurements were significantly higher than that of Pentacam (both P < 0.0001). The ACD measurements also demonstrated a strong positive correlation, with r values of 0.959 between MS-39 and Sirius, 0.947 between MS-39 and Pentacam, and 0.932 between Sirius and Pentacam (both P < 0.0001). In terms of ICL size selection based on the measurements from the three devices, the12.6mm size was the most frequently selected, while the 13.7mm size was the least common, the distribution of size selections across the devices was similar. Conclusions: MS-39 demonstrated strong positive correlation with both Sirius and Pentacam for WTW and ACD measurements, indicating that the results can be considered clinically interchangeable. Furthermore, the outcomes derived from MS-39 for ICL size selection were closely aligned with those from Sirius and Pentacam, suggesting its clinical feasibility.

陕西省重点研发计划(2023-YBSF-568)；陕西省自然科学基金(2024JC-YBQN-0962)；西安交通大学第一附属医院普通新医疗新技术项目(XJYFY-2023YL10)