颈内动脉狭窄与缺血性眼部疾病的相关关系探究
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Relationship between carotid artery stenosis and ischemic ocular diseases
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    摘要:

    目的:探讨颈内动脉狭窄与缺血性眼部疾病的关系。

    方法:收集2010-11/2014-05入住我院的30例37眼缺血性眼部疾病患者的临床资料,对其行眼底荧光素血管造影(FFA)、眼部血管经颅多普勒超声(TCD)、颈部血管彩色超声多普勒血流成像(CDFI)、颈部CT血管造影(CTA)及颈动脉数字减影血管造影(DSA)等检查,然后对缺血性眼部疾病患者眼部症状、眼部表现、FFA检查结果进行分析; 比较眼动脉收缩期峰值血流速度(peak systolic velocity,PSV)和阻力指数(resistance index,RI)、视网膜中央动脉PSV及RI; 患侧颈动脉内中膜厚度(IMT)与眼动脉、视网膜中央动脉PSV及RI的相关性; 患侧颈内动脉斑块性质与眼动脉PSV及RI的相关性; 患侧颈内动脉斑块性质与视网膜中央动脉的PSV及RI相关性。

    结果:眼部症状:一过性黑矇、视力降低、眼前闪光、眼部及周围疼痛发生率分别为75.7%,83.8%,51.4%及32.4%; 眼部体征:以视网膜静脉扩张、视网膜点片状出血、动脉狭窄及棉絮斑等为主要体征; 患侧与健侧眼动脉PSV及RI值差异均具有统计学意义(P<0.05); 患侧与健侧视网膜中央动脉PSV及RI值差异均具有统计学意义(P<0.05); 患侧IMT与眼动脉、视网膜中央动脉PSV及RI值无相关性(P>0.05); 患侧颈内动脉斑块性质与眼动脉PSV及RI值无相关性(P>0.05); 患侧颈内动脉斑块性质与视网膜中央动脉的PSV及RI值无相关性(P>0.05)。

    结论:缺血性眼部疾病的发病与颈内动脉狭窄具有非常紧密的关联性,临床上可将颈内动脉狭窄程度作为眼部疾病诊疗的重要依据。

    Abstract:

    AIM: To investigate the relationship between carotid artery stenosis and ischemic ocular diseases.

    METHODS: The clinical data of 30 cases(37 eyes)of patients with ischemic eye diseases were collected from November 2010 to May 2014, and they were accepted the fundus fluorescein angiography(FFA), transcranial Doppler(TCD)ultrasonic blood vessels of the eye, neck vascular color Doppler flow imaging(CDFI), the neck CT angiography(CTA)and carotid artery digital subtraction angiography(DSA)examination, and then the ischemic eye disease patients with ocular symptoms were analyzed. The peak systolic velocity(PSV)and resistance index(RI)of ophthalmic artery and central retinal artery were compared. Correlation between the internal carotid artery intima-media thickness(IMT)and ophthalmic artery, central retinal artery PSV and RI correlation risk; ipsilateral internal carotid artery plaque and ophthalmic artery PSV and RI; PSV and RI associated ipsilateral internal carotid artery plaque and central retinal artery were analyzed.

    RESULTS: Eye symptoms: a black dim, reduced vision, the eyes flash, and around the eye pain were 75.7%, 83.8%, 51.4% and 32.4%; The eye signs: the dilatation of retinal vein, retinal hemorrhage, arterial stenosis and cotton spot and the contralateral side were regarded as main signs. Ophthalmic artery PSV and RI value of the differences were statistically significant(P<0.05); The contralateral side of the central retinal artery PSV and RI value of the differences were statistically significant(P<0.05); The ipsilateral internal carotid artery IMT and ophthalmic artery, central retinal artery PSV and RI were not correlated(P>0.05); The ipsilateral internal carotid artery plaque and ophthalmic artery PSV had no correlation with RI values(P>0.05); PSV and RI and the ipsilateral internal carotid artery plaque and central retinal artery had no correlation(P>0.05).

    CONCLUSION: The incidence of ischemic eye diseases and internal carotid artery stenosis is associated with very close, the clinical can regard the degree of internal carotid artery stenosis as an important basis for diagnosis and treatment of eye diseases.

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陈前,赵洪超.颈内动脉狭窄与缺血性眼部疾病的相关关系探究.国际眼科杂志, 2015,15(1):108-111.

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  • 收稿日期:2014-08-15
  • 最后修改日期:2014-12-22
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  • 在线发布日期: 2014-12-30
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